ADI1 antibody

Catalog No. ABIN7072888

This anti-ADI1 antibody is a Rabbit Polyclonal antibody detecting ADI1 in IHC and IF. Suitable for Rat.

Quick Overview for ADI1 antibody (ABIN7072888)

Target: ADI1 (Acireductone Dioxygenase 1 (ADI1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADI1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ADI1 Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinantproteincorrespondingto Human ADI1

Application Details

Application Notes: IHC/IF (R) 1:800-1:3000/1:600-1:1200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ADI1

Target: ADI1 (Acireductone Dioxygenase 1 (ADI1))

Alternative Name: ADI1

Background: ADI1(acireductone dioxygenase 1 ) is also named as SIPL, ARD, APL1, HMFT1638, MTCBP-1, FLJ10913, MTCBP1 and belongs to the acireductone dioxygenase (ARD) family. It catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).The downregulation of ADI1 protein expression in human prostate cancer specimens argues that ADI1 potentially inhibits the growth that occurs during prostate cancer progression(PMID:17786183). It has 2 isoforms produced by alternative splicing.

Gene ID: 55256

UniProt: Q562C9

Pathways: Methionine Biosynthetic Process